Impact of Preoperative Versus Postoperative Chemotherapy on the Extent and Number of Surgical Procedures in Patients Treated in Randomized Clinical Trials for Breast Cancer

摘要

Volume of breast tissue resected to achieve negative margins and number of surgical procedures undertaken were compared between patients who underwent preoperative chemotherapy and those who underwent postoperative chemotherapy for breast cancer. Volume of breast tissue resected was significantly less in patients with T2 and T3 tumors who received preoperative chemotherapy than in those who received postoperative chemotherapy.